Omni La Mansión del Rio
112 College Street
San Antonio, Texas 78205

48 Hours in San Antonio Riverwalk Itinerary

The Alamo

Nestled along San Antonio’s historic River Walk (or Paseo del Rio), Omni La Mansión del Rio is the ideal base for exploring the city’s greatest attractions. Although the first business along this urban walkway opened in 1946, the San Antonio River has been a central part of the city’s development since the 1500s, providing guests with the opportunity to step back in time during their stay at the romantic Spanish-style hacienda. Those looking to explore San Antonio’s history, as well as its modern charm, will find inspiration in our two-day itinerary highlighting the city’s best cuisine, entertainment and more.

Book Your Activities

Day One


Start your morning with breakfast on the River Walk at Four Brothers restaurant and enjoy a combination of Southern and South Texas cuisine. Choose from savory dishes like Huevos Rancheros and Smoked Brisket Benedict or opt for something a little sweeter like Vanilla Cream French Toast or a Sticky Bourbon & Pecan Cinnamon Bun.

After you’ve finished breakfast, choose from several sightseeing options, all walkable from the Omni La Mansion del Rio. Explore The Alamo, the most visited historic landmark in all of Texas. Then travel upriver to visit The San Antonio Museum of Art, the riverfront building that houses this museum was formerly a brewery, giving it a unique aesthetic in which to view European, Asian, Oceanic, Latin American, and American ancient and contemporary art.

San Antonio Museum of Art


Continue your tour of local museums with a trip to the McNay Art Museum, the first modern art museum in Texas. Housed in a Spanish Colonial Revival abode, the museum’s collection consists of 20,000 pieces of art, including paintings, sculptures, and art glass from the 19th century on.

When lunchtime rolls around, stop by the Pearl Brewery for lunch. Although it's not actually the site of a brewery today, it is a culinary and cultural destination along the river and is the perfect spot to enjoy lunch. Pay a visit to Southerleigh Fine Food and Brewery, which houses a custom manufactured brewery that brings brewing back to the Pearl offering 15 different beers on tap.

Southerleigh Fine Food and Brewery


In the evening, head across the river to Ostra and indulge in fresh seafood and riverfront views. Don’t miss a chance to try the acclaimed Oyster Bar, which includes a variety of the freshest oysters, clams, crab, shrimp, and ceviche. Ostra offers a full wine list and specialty tequilas. With more than 70 labels, Ostra houses the largest selection of tequilas and Mezcals in downtown San Antonio.

Ostra Entrance

Day Two


If it’s a luxurious breakfast you seek, the Guenther House can’t be beat. A blend of art nouveau and Victorian, the house has been operating as a restaurant and museum since 1988. The solid copper light fixtures, ceramic tile flooring and stained-glass panels featuring an ivy design make for a quaint setting in which to dine on buttermilk biscuits, sweet cream waffles, country sausage or breakfast tacos.

While in the city’s King William District, explore this historic part of town where homes from the 19th-century have been repurposed and converted into shops, museums, and art galleries. These fashionable structures are just as enchanting to walk past as they are to enter. Two to note are Villa Finale and the Edward Steves Homestead, both of which you can tour.

For a more casual spot, hop over to La Panaderìa Bakery and Café for delicious handmade bread and pan dulce inspired by Mexico’s Golden Era. Panderìa’s unique approach to breadmaking includes a 48-hour fermentation process that results in artisan baked goods unlike any other.

Edward Steves Homestead


You can’t miss touring the San Antonio Missions. This UNESCO site houses four missions—Concepción, San José, San Juan and Espada—each provide the perfect glimpse into the city’s history. The ancient structures are beautifully constructed and full of information.

If a relaxing afternoon is what you’re after, opt to head back to the hotel. Four Brothers offers a combination of Southern and South Texas cuisine with Latin and French influences such as a basil crusted Branzino served over pecan risotto or Filet Mignon served with purple potatoes, spinach purée, and café de Paris butter. Make sure to start your meal with the delicious Bexar Cornbread and BBQ Glazed Brussel Sprouts before treating yourself to one of their delicious entrees and cocktails.

Spend the rest of the afternoon indulging in a treatment at Mokara Spa. The only Forbes Four-Star Spa in the city, Mokara Spa is considered one of the best spas in Texas, offering a complete menu of spa treatments and services guaranteed to restore the body and mind.



There are endless dinner options within walking distance of the hotel. Indulge in a 48 oz Tomahawk ribeye at Four Brothers or opt for the Market Big Fish, fried whole market fish served with tri-color peppers, and cilantro rice. Don’t forget Dessert! The Meyer Lemon Crème Brulé is a must try!

If you want to wander a little farther for dinner, try Bohanan’s Prime Steaks and Seafood. A chic eatery serving American fare in an old – world setting with a cocktail lounge, patio & live jazz.

Once you’ve eaten, enjoy a few more nighttime activities. Four Brothers offers craft cocktails and Live Music! If you’re looking for a more relaxing atmosphere, pop into El Colegio for cocktails and bar bites.

Four Brothers

If you have more time...

Make your way to the Historic Market Square and experience a three-block outdoor plaza lined with shops and restaurants. Market Square is the largest Mexican market in the United States. The "El Mercado" section has 32 specialty shops, and the "Farmer's Market Plaza" section has 80.

Or, if you’re looking for something the whole family will enjoy, make a trip to the San Antonio Zoo, Six Flags Fiesta Texas, or SeaWorld San Antonio for a fun filled day.

San Antonio Market